Large Percentage of Deaths by Drug Overdose May be Suicides

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Between 25 and 45 percent of deaths by overdose may be suicides, according to the immediate past president of the American Psychiatric Association. Dr. Maria Oquendo told NBC News the opioid epidemic is occurring at the same time suicides have risen to a 30-year high. One study of overdoses from prescription opioids found almost 54 percent were unintentional. The rest were either suicide attempts or undetermined, the article notes. Few doctors are looking for a connection between opioid addiction and suicides, Dr. Oquendo said. “They are not monitoring it,” she said. “They are probably not assessing it in the kinds of depths they would need to prevent some of the deaths.”

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APA Releases New Practice Guideline on AUD Pharmacotherapy

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The American Psychiatric Association (APA) recently released a new practice guideline for the pharmacological treatment of alcohol use disorder (AUD). Despite the high prevalence of AUD and its significant public health consequences, patients with this disorder remain undertreated. The guideline aims to increase physician and public knowledge on the effectiveness and risks of the five medications that may be used for the treatment of AUD: acamprosate, disulfiram, gabapentin, naltrexone, and topiramate. Of these five, naltrexone and acamprosate have the best available evidence related to their benefits, and both have minimal side effects. As such, they should be considered the preferred pharmacological options for patients with moderate to severe AUD who want to reduce drinking or achieve abstinence. However, acamprosate should be avoided in patients with significant renal impairment, and naltrexone should be avoided in patients with acute hepatitis or liver failure, or in patients currently taking opioids or who may be...

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